
A New Class of Drug
The NANO DRUG DELIVERY SYSTEM
Pharmachal's Nano Drug Delivery System (the "NDDS") is an internationally-patented, successfully clinically-trialled, drug-in-oil mini-emulsion able to deliver a wide range of small molecule drugs and other active ingredients topically, sublingually, nasally or rectally in the form of a spray, cream or patch, or intravenous application.
​
The mean particle size of NDDS is ~1μm, allowing a range of drugs to be delivered at a cellular level, providing new methods for delivering existing drugs and, in many cases, replacing injections. Clinical studies have demonstrated elevated bioavailability with lower doses and lower toxicity.
​
The NDDS's global patents cover a wide range of APIs and bioactive ingredients including peptides, mRNA, analgesics, vaccines, botanicals, nutrients and more. They provide decades of coverage to the company.
​
Pharmachal is working on a suite of products, including its NOPAYNE lidocaine spray, the I-Derm lidocaine patch and the Proctorhoid enema for post-rectal surgery. The company is also incorporating Rambam Medtech's pro-coagulation peptide API into the formula.
​
​


How small is 1μm?
​
Pharmachal's NDDS mini-emulsion technology has a particle size of less than 1μm - down to 0.3μm and smaller. This explains why it can produce superior bioavailability, delivering similar results to prescription strength drugs with lower-dose, safer over-the-counter strength formulations. Watch the video to see just how low we can go.